I’m interested in the development of novel therapeutics with a current focus on cyclic peptides. I use molecular dynamics and enhanced sampling methods (Replica Exchange with Solute Tempering) to investigate the conformations of cyclic peptides and I am working to better understand the structural information contained within common experimental measurements (NMR chemical shifts, NOE’s and Ion Mobility Collision Cross Sections).

Working in collaboration with the Tavassoli Group, University of Southampton
Funded by the EPSRC and Astra Zeneca
Twitter: @JW_Easton

I am also the 2020 University of Southampton 3MT Champion!